Since I began to use CUDA at 44,1 I was able to load like five great reverbs (with lots of kernels: from VNXT to long springs) without problem. Since I'm mixing at 96 I'm having some problems, though. CPU is fine when using some Nebula Reverb Core3 (I'm with one single computer but with Server), I can load a considerable ammount of programs without making suffer my CPU, but when I load one single instance of Nebula CUDA (you know, a copy of the Reverb one but changing the XML with a longer DSPBUFFER and with the Optfreqd @ 15) I'm suffering spikes and CPU issues even with one kernel programs. If I unload the CUDA instance, my CPU goes from 120% to 30% aproximately. Not normal, IMHO.
I don't know if it's an issue of Server with CUDA or if 96 is too much for my computer, but since I'm with an i7 2600 and 16GB RAM I don't think that I'm having a really big problem regarding my computer resources.